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Orringer Lab

Publications

2026

Neurosurgical FocusReview

Intraoperative artificial intelligence for brain tumor surgery: from tissue diagnosis to real-time surgical guidance

Goff NK, Markert JE, Park M, Springer A, Chen AM, Orringer DA

Journal of Neurosurgery: Case LessonsArticle

Awake craniotomy with functional mapping for recurrent high-grade IDH-mutant glioma during pregnancy: illustrative case

Fang CS, Weiss H, Bhanja D, Penfield CA, Ard J, Orringer DA

medRxivPreprint

SIGNAL: A Scalable, Real-World Model for Rapid Intraoperative Molecular Classification of Gliomas Using Stimulated Raman Histology

Goff NK, Markert JE, Reinecke D, et al.

NeurosurgeryArticle

Anatomic Predilection of Isocitrate Dehydrogenase-Mutant Gliomas: A Multi-Institutional Spatial Analysis

Park M, Weiss H, Harake ES, et al.

2025

MedArticle

Ultra-rapid droplet digital PCR enables intraoperative tumor quantification

Murphy ZR, Bianchini EC, Smith A, et al.

2024

Neuro-OncologyArticle

Fast intraoperative detection of primary central nervous system lymphoma and differentiation from common central nervous system tumors using stimulated Raman histology and deep learning

Reinecke D, Maarouf N, Smith A, et al.

NatureArticle

Foundation models for fast, label-free detection of glioma infiltration

Kondepudi A, Pekmezci M, Hou X, et al.

Nature Biomedical EngineeringArticle

Localization of protoporphyrin IX during glioma-resection surgery via paired stimulated Raman histology and fluorescence microscopy

Nasir-Moin M, Wadiura LI, Sacalean V, et al.

2023

Nature MedicineArticle

Artificial-intelligence-based molecular classification of diffuse gliomas using rapid, label-free optical imaging

Hollon T, Jiang C, Chowdury A, et al.